Research Articles

(* Corresponding Author)


Yash Pal Singh, Himanshu Rai, Gourav Singh, Gireesh Kumar Singh, Saroj Kumar, Sunil Mishra, S Srikrishna, Gyan Modi*. 2021. “A Review on Ferulic Acid and Analogs Based Scaffolds for the Management of Alzheimer's Disease.” European Journal of Medicinal Chemistry, 215: 113278. (IF: 6.514)


Simran Rastogi, Vaibhav Sharma, Prahalad Singh Bharti, Komal Rani, Gyan P. Modi, Fredrik Nikolajeff, and Saroj Kumar*. 2021. “The Evolving Landscape of Exosomes in Neurodegenerative Diseases: Exosomes Characteristics and a Promising Role in Early Diagnosis.” International Journal of Molecular Sciences 22 (1): 440. (IF: 5.923)


Komal Rani, Simran Rastogi, Poorvi Vishwakarma, Prahalad Singh Bharti, Vaibhav Sharma, Km Renu, Gyan P. Modi, Venugopalan Y. Vishnu, Prashun Chatterjee, Aparajit Ballav Dey, Fredrik Nikolajeff, and Saroj Kumar*. 2021. “A Novel Approach to Correlate the Salivary Exosomes and Their Protein Cargo in the Progression of Cognitive Impairment into Alzheimer’s Disease.” Journal of Neuroscience Methods 347 (January): 108980. (IF: 2.390)


Lakshay Malhotra, Harsh K. V. Goyal, Sunita Jhuria, Kapil Dev, Saroj Kumar, Manoj Kumar, Punit Kaur, and Abdul S. Ethayathulla*. 2021. “Curcumin Rescue P53Y220C in BxPC-3 Pancreatic Adenocarcinomas Cell Line: Evidence-Based on Computational, Biophysical, and in Vivo Studies.” Biochimica et Biophysica Acta (BBA) - General Subjects 1865 (2): 129807. (IF: 3.770)


Vaibhav Sharma, Alagiri Srinivasan, Fredrik Nikolajeff, Saroj Kumar*. 2021. "Biomineralization Process in Hard Tissues: The Interaction Complexity within Protein and Inorganic Counterparts". Acta Biomaterialia. 120: 20-37. (IF: 8.947)


Simran Rastogi, Komal Rani, Fredrik Nikolajeff, and Saroj Kumar*. 2020. “Finding a Novel Method to Understand the Role of Salivary Exosome in Progression of Cognitive Impairment to Alzheimer’s Disease.” Alzheimer’s & Dementia 16 (S4): e041920. (IF: 21.566)


Rajkumar Kulandaisamy, Tushar Kushwaha, Vikas Kumar, Soumya De, Saroj Kumar, Santosh Kumar Upadhyay, Manoj Kumar, Krishna K. Inampudi*. 2020. "Characterization of active/binding site residues of peptidyl-tRNA hydrolase using biophysical and computational studies". International Journal of Biological Macromolecules. 159: 877-885. (IF: 6.953)


Vaibhav Sharma, Simran Rastogi, Kaushal Kumar Bhati, Alagiri Srinivasan, Ajoy Roychoudhury, Fredrik Nikolajeff, and Saroj Kumar*. 2020. “Mapping the Inorganic and Proteomic Differences among Different Types of Human Teeth: A Preliminary Compositional Insight.” Biomolecules 10 (11): 1540.  (IF: 4.879)


Komal Rani, Mitali Tyagi, Mohit Majumdar, Akanksha Singh, Annaian Shanmugam, Krishna Dalal, Manoj Pillai, Gourinath Samudrala, Saroj Kumar, Alagiri Srinavasan*. 2020. “Accelerated identification of serine racemase inhibitor from Centella asiatica"Scientific Reports. 10 (1): 4640. (IF: 4.379)


Javeed Ahmad, Mohd Khubaib, Javaid Ahmad Sheikh, Rita Pancsa, Saroj Kumar, A. Srinivasan, M. Madan Babu, Seyed E. Hasnain*, and Nasreen Z. Ehtesham*. 2020. “Disorder-to-Order Transition in PE-PPE Proteins of Mycobacterium Tuberculosis Augments the pro-Pathogen Immune Response.” FEBS Open Bio. 10: 70-85. (IF: 2.693)


Komal Rani, Ranjan Mukherjee, Ekta Singh, Sanjeev Kumar, Vaibhav Sharma, Poorvi Vishwakarma, Prahalad Singh Bharti, Fredrik Nikolajeff, Ashok Kumar Dinda, Vinay Goyal and Saroj Kumar*. 2019. “Neuronal Exosomes in Saliva of Parkinson’s Disease Patients: A Pilot Study.” Parkinsonism & Related Disorders. 67: 21-23. (IF: 4.36)


Vaibhav Sharma, Komal Rani, Ajoy Roychoudhury, Amita Chawla, Fredrik Nikolajeff and Saroj Kumar*2019. "Novel Insights into Regulation of Human Teeth Biomineralization: Deciphering the Role of Post-Translational Modifications in a Tooth Protein Extract." International Journal of Molecular Sciences. 20 (16): 4035. (IF: 5.923)


Vaibhav Sharma, Alagiri Srinivasan, Ajoy Roychoudhury, Komal Rani, Mitali Tyagi, Kapil Dev, Fredrik Nikolajeff, and Saroj Kumar*. 2019. “Characterization of Protein Extracts from Different Types of Human Teeth and Insight in Biomineralization.” Scientific Reports 9 (1): 9314. (IF: 4.379)


Saroj Kumar*. 2019. “Infrared Spectroscopy Could Be a Diagnostic Tool in Dermatology.” The British Journal of Dermatology 180 (3): 459–60. (IF: 9.302)


Das, Uddipan, Ekta Singh, Sudhaker Dharavath, Udaya Kumar Tiruttani Subhramanyam, Ravi Kant Pal, Ramachandran Vijayan, Saji Menon, Saroj Kumar, Samudrala Gourinath, and Alagiri Srinivasan. 2019. “Structural Insights into the Substrate Binding Mechanism of Novel ArgA from Mycobacterium Tuberculosis.” International Journal of Biological Macromolecules 125 (March): 970–78. (IF: 6.953)


Saibu, Yusuf, Saroj Kumar, Ankur Jamwal, Derek Peak, and Som Niyogi. 2018. “A FTIRM Study of the Interactive Effects of Metals (Zinc, Copper and Cadmium) in Binary Mixtures on the Biochemical Constituents of the Gills in Rainbow Trout (Oncorhynchus Mykiss).” Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP 211 (September): 48–56. (IF: 3.228)


Kumar, Saroj*, Alagiri Srinivasan, and Fredrik Nikolajeff. 2018. “Role of Infrared Spectroscopy and Imaging in Cancer Diagnosis.” Current Medicinal Chemistry 25 (9): 1055–72. (IF: 4.53)


Kumar, Saroj*, Xia Liu, Ferenc Borondics, Qunfeng Xiao, Renfei Feng, Erik Goormaghtigh, and Fredrik Nikolajeff. 2017. “Insights into Biochemical Alteration in Cancer-Associated Fibroblasts by Using Novel Correlative Spectroscopy.” Chemistry Open 6 (1): 149–57. (IF: 2.911)


Divekar, Monali Trimbak, Chithra Karunakaran, Rachid Lahlali, Saroj Kumar, Vellaichamy Chelladurai, Xia Liu, Ferenc Borondics, Saravanan Shanmugasundaram, and Digvir Singh Jayas. 2017. “Effect of Microwave Treatment on the Cooking and Macronutrient Qualities of Pulses.” International Journal of Food Properties 20 (2): 409–22. (IF: 2.727)


Lahlali, Rachid, Tao Song, Mingguang Chu, Fengqun Yu, Saroj Kumar, Chithra Karunakaran, and Gary Peng. 2017. “Evaluating Changes in Cell-Wall Components Associated with Clubroot Resistance Using Fourier Transform Infrared Spectroscopy and RT-PCR.” International Journal of Molecular Sciences 18 (10). (IF: 5.923)


Lahlali, Rachid, Saroj Kumar, Lipu Wang, Li Forseille, Nicole Sylvain, Malgorzata Korbas, David Muir, et al. 2016. “Cell Wall Biomolecular Composition Plays a Potential Role in the Host Type II Resistance to Fusarium Head Blight in Wheat.” Frontiers in Microbiology 7 (June). (IF: 5.640)


Caine, Sally, Mark J. Hackett, Huishu Hou, Saroj Kumar, Jason Maley, Zurab Ivanishvili, Brandon Suen, et al. 2016. “A Novel Multi-Modal Platform to Image Molecular and Elemental Alterations in Ischemic Stroke.” Neurobiology of Disease 91: 132–42. (IF: 5.996)


Kumar, Saroj*, Rachid Lahlali, Xia Liu, and Chithra Karunakaran. 2016. “Infrared Spectroscopy Combined with Imaging: A New Developing Analytical Tool in Health and Plant Science.” Applied Spectroscopy Reviews 51 (6): 466–83. (IF: 5.917)


Lahlali, Rachid, Tao Song, Mingguang Chu, Fengqun Yu, Linda Mcgregor, B Gossen, Saroj Kumar, Chithra Karunakaran, and Gary Peng. 2016. “Investigation on the Role of Molecular Composition and Lignification of Canola Plant Cell Wall in Resistance Mechanisms Associated with CR Gene Rcr1.” Phytopathology 106 (12): 145.


Ukkonen, H., S. Kumar*, J. Mikkonen, T. Salo, S. P. Singh, A. P. Koistinen, E. Goormaghtigh, and A. M. Kullaa. 2015. “Changes in the Microenvironment of Invading Melanoma and Carcinoma Cells Identified by FTIR Imaging.” Vibrational Spectroscopy 79 (July): 24–30. (IF: 2.507)


Jiang, Yunfei, Rachid Lahlali, Chithra Karunakaran, Saroj Kumar, Arthur R. Davis, and Rosalind A. Bueckert. 2015. “Seed Set, Pollen Morphology and Pollen Surface Composition Response to Heat Stress in Field Pea.” Plant, Cell & Environment 38 (11): 2387–97. (IF: 7.228)


Lahlali, Rachid, Wang, L, Kumar, Saroj, Karunakaran, Chithra, Fobert, PR, Peng, Gary and Hallin, Emil L. 2015. Use of Fourier transform-infrared spectroscopy as a new method to study host resistance mechanism to fusarium head blight [Fusarium graminearum]. Canadian Journal of Plant Pathology. 37 (2): 248-252. (IF: 2.442)


Kumar, Saroj*. 2014. “Infrared Difference Spectroscopy as a Physical Tool to Study Biomolecules.” Applied Spectroscopy Reviews 49 (3): 187–200. (IF: 5.917)


Kumar, Saroj*, Thankaraj Salammal Shabi, and Erik Goormaghtigh. 2014. “A FTIR Imaging Characterization of Fibroblasts Stimulated by Various Breast Cancer Cell Lines.” PLOS ONE, 9 (11): e111137. (IF: 3.240)


Lahlali, Rachid, Yunfei Jiang, Saroj Kumar, Chithra Karunakaran, Xia Liu, Ferenc Borondics, Emil Hallin, and Rosalind Bueckert. 2014. “ATR–FTIR Spectroscopy Reveals Involvement of Lipids and Proteins of Intact Pea Pollen Grains to Heat Stress Tolerance.” Frontiers in Plant Science. 5:747 (IF: 5.753)


Li, Chenge, Saroj Kumar, Cédric Montigny, Marc le Maire, and Andreas Barth. 2014. “Quality Assessment of Recombinant Proteins by Infrared Spectroscopy. Characterisation of a Protein Aggregation Related Band of the Ca2+-ATPase.” The Analyst 139 (17): 4231–40. (IF: 4.616)


Salammal, Shabi Thankaraj, Jean-Yves Balandier, Saroj Kumar, Erik Goormaghtigh, and Yves Henri Geerts. 2014. “Influence of Solubilizing Group Removal Rate on the Morphology and Crystallinity of a Diketopyrrolopyrrole-Based Compound.” Crystal Growth & Design 14 (1): 339–49. (IF: 4.076)


Kumar, Saroj, Chenge Li, Cédric Montigny, Marc le Maire, and Andreas Barth. 2013. “Conformational Changes of Recombinant Ca2+-ATPase Studied by Reaction-Induced Infrared Difference Spectroscopy.” The FEBS Journal 280 (21): 5398–5407. (IF: 5.542)


Valdivia, Alejandro Arbesú, Andreas Barth, Yamilet Romero Batista, and Saroj Kumar*. 2013. “Characterization of Recombinant Antibodies for Cancer Therapy by Infrared Spectroscopy.” Biologicals: Journal of the International Association of Biological Standardization 41 (2): 104–10. (IF: 1.856)


Kumar, S., C. Desmedt, D. Larsimont, C. Sotiriou, and E. Goormaghtigh. 2013. “Change in the Microenvironment of Breast Cancer Studied by FTIR Imaging.” Analyst 138 (14): 4058–65. (IF: 4.616)


Kumar, Saroj, Nadejda Eremina, and Andreas Barth. 2012. “Detection of Ligand Binding to Proteins through Observation of Hydration Water.” The Journal of Physical Chemistry. B 116 (48): 13968–74. (IF: 2.991)


Kumar, Saroj* and Barth, Andreas. 2011. “Effects of Ions on Ligand Binding to Pyruvate Kinase: Mapping the Binding Site with Infrared Spectroscopy.” The Journal of Physical Chemistry. B 115 (20): 6784–89. (IF: 2.991)


Kumar, Saroj* and Barth, Andreas. 2011. “The Allosteric Effect of Fructose Bisphosphate on Muscle Pyruvate Kinase Studied by Infrared Spectroscopy.” The Journal of Physical Chemistry. B 115 (39): 11501–5. (IF: 2.991)


Kumar, Saroj and Barth, Andreas. 2010. “Following Enzyme Activity with Infrared Spectroscopy.” Sensors 10 (4): 2626–37. (IF: 3.576)


Kumar, Saroj and Barth, Andreas. 2010. “Phosphoenolpyruvate and Mg2+ Binding to Pyruvate Kinase Monitored by Infrared Spectroscopy.” Biophysical Journal 98 (9): 1931–40. (IF: 4.033)


Rudbeck, Maria E., Saroj Kumar, Maria-Andrea Mroginski, Sten O. Nilsson Lill, Margareta R. A. Blomberg, and Andreas Barth. 2009. “Infrared Spectrum of Phosphoenol Pyruvate: Computational and Experimental Studies.” The Journal of Physical Chemistry. A 113 (12): 2935–42. (IF: 2.781)


Krasteva, Maria, Saroj Kumar, and Andreas Barth. 2006. “A Dialysis Accessory for Attenuated Total Reflection Infrared Spectroscopy.” Research article. Journal of Spectroscopy. 2006. (IF: 1.914)


"A multifunctional Diarylurea-hydroxyamidine based compound for treatment of Alzheimer's disease". Gyan Prakash Modi, Yash Pal,  C. Praveen Kumar, Meenu Yadav, Gauri Shankar, Gourav Singh, Saroj Kumar, S Srikrishna. TEMP/E-1/1680/2021-DEL, 12 Jan, 2021


S Kumar. Infrared spectroscopy: Method development and ligand binding to pyruvate kinase. 2011, pp 1-57, ISBN: 978-91-7447-297-4