
S Kumar Lab

Research Articles
(* Corresponding Author)
Under Publication
Abhay Mishra, Sadaqa Zehara, Sandeep Mathur, Piyush Ranjan, Atul Batra, Krishna Kishore Inampudi, Fredrik Nikolajeff, Saroj Kumar*. 2023. Plasma-derived exosomes to reveal the breast cancer progression: an FTIR analysis. Analyst (Under Review, AN-ART-08-2023-001446). (IF: 5.227)
Rishabh Singh, Sanskriti Rai, Prahalad Singh Bharti, Sadaqa Zehara, Krishna Kishore Inampudi, Vishnu VY, Prasun Chatterjee, Fredrik Nikolajeff, Saroj Kumar*. 2023. “Understanding the inflammation and synaptic dysfunction in Alzheimer's disease through the lens of small extracellular vesicles”. Frontiers in Immunology. (Manuscript Submitted).
Priya Kumari Gorai, Prahalad Singh Bharti, Shashi Kumar, Girish Rajacharya, Sabyasachi Bandyopadhyay, Sujoy Pal, Renu Dhingra, Rakesh Kumar, Fredrik Nikolajeff, Saroj Kumar*, Neerja Rani*. 2023. “C1QA and COMP: Plasma-based Biomarkers for Early Diagnosis of Pancreatic Neuroendocrine Tumors”. International Journal of Biological Macromolecules. (Under Review, IJBIOMAC-D-23-11168) (IF: 8.2)
Priya Kumari Gorai, Simran Rastogi, Prahalad Singh Bharti, Shipra Agarwal, Sujoy Pal, Mehar Chand Sharma, Rakesh Kumar, Fredrik Nikolajeff, Saroj Kumar*, Neerja Rani*. 2023. “Plasma-derived extracellular vesicles reveal pancreatic neuroendocrine tumors.” Translational Oncology. (Under Review, TRANON-D-23-01483) (IF: 5.0)
Himanshu Rai, Rishabh Singh, Prahalad Singh Bharti, Prabhat Kumar, Sanskriti Rai, Tanmay Varma, Brijesh Singh Chauhan, Aishwarya Nilakhe, Joy Debnath, Vijay Mishra, Sarika Gupta, Sairam Krishnamurthy, Jian Yang, Prabha Garg, Saripella Srikrishna, Saroj Kumar, Gyan Modi*. 2023. “Rhodanine composite fluorescence probes to detect amyloid-beta aggregated species in Alzheimer's disease models”. Research Square (Pre-print) https://doi.org/10.21203/rs.3.rs-2721179/v1
Deepa Singh, Tushar Kushwaha, Rajkumar Kulandaisamy, Vikas Kumar, Kamal Baswal, Saras H Tiwari, Arkadyuti Ghorai, Manoj Kumar, Saroj Kumar, Aparoy Polamarasetty, Deepak Sehgal, Madhumohan R Katika, Suresh Gadde, Marceline Côté, Sarala R Kayampeta, Mohan B Appaiahgari*, Krishna K Inampudi*. 2023. “Interaction of SCoV-2 NSP7 or NSP8 alone with NSP12 causes constriction of the RNA entry channel: Implications for novel RdRp inhibitor drug discovery”. bioRxiv (Pre-print). https://doi.org/10.1101/2023.07.26.550660
Singh G, Kesharwani P, Kumar B, Mishra I, Kumar S, Modi G. 2022. “Ferroptosis a Futuristic Roadmap for Cancer and Alzheimer’s Disease.” SSRN Electronic Journal (Pre-Print). https://dx.doi.org/10.2139/ssrn.4091174
Published
Simran Rastogi, Komal Rani, Sanskriti Rai, Rishabh Singh, Vaibhav Sharma, Prahalad Singh Bharti, Jyoti Sahu, Vrinda Kapoor, Poorvi Vishwakarma, Sumit Garg, Shivajirao Lahu Gholap, Krishna Kishore Inampudi, Gyan Prakash Modi, Neerja Rani, Madhavi Tripathi, Achal Srivastava, Roopa Rajan, Fredrik Nikolajeff, Saroj Kumar*. 2023. “Fluorescence tagged salivary exosomes as a nano tool in early diagnosis of Parkinson’s disease”. BMC Medicine. 21 (1): 335. (IF: 11.806)
Sanskriti Rai, Prahalad Singh Bharti, Rishabh Singh, Simran Rastogi, Komal Rani, Gyan Prakash Modi, Krishna Kishore Inampudi, Hem Chandra Pandey, Sanjay Yadav, Roopa Rajan, Fredrik Nikolajeff, Saroj Kumar*. 2023. “Circulating plasma miR-23b-3p as a biomarker target for Idiopathic Parkinson’s disease: comparison with small extracellular vesicle miRNA”. Frontiers in Neuroscience. (Accepted) (IF: 5.15)
Nilisha Rastogi, Sheeba Zarin, Anwar Alam, Guruprasad Varma Konduru, P. Manjunath, Abhay Mishra, Saroj Kumar, Hampapathalu Adimurthy Nagarajaram, Seyed Ehtesham Hasnain, and Nasreen Zafar Ehtesham. 2023. “Structural and Biophysical Properties of Therapeutically Important Proteins Rv1509 and Rv2231A of Mycobacterium Tuberculosis.” International Journal of Biological Macromolecules. 245: 125455. (IF: 8.2)
Sunil Kumar, Iqra Ali, Faheem Abbas, Nimra Khan, Manoj K. Gupta, Manoj Garg, Saroj Kumar, and Deepak Kumar. 2023. “In-Silico Identification of Small Molecule Benzofuran-1,2,3-Triazole Hybrids as Potential Inhibitors Targeting EGFR in Lung Cancer via Ligand-Based Pharmacophore Modeling and Molecular Docking Studies.” In Silico Pharmacology 11 (1): 20.
Simran Rastogi, Komal Rani, Vaibhav Sharma, Prahalad Singh Bharti, Krishna Deo, Veena Jain, Aditi Nanda, Saroj Kumar*, Dheeraj Kumar Koli*. 2023. “Osteogenic markers in perimplant crevicular fluid (PICF) in immediate and delayed loaded dental implants: A randomized controlled trial”. Clinical Implant Dentistry and Related Research. 2023; 1- 9. (IF: 4.259)
Sunil Kumar, Faheem Abbas, Iqra Ali, Manoj K. Gupta, Saroj Kumar, Manoj Garg, and Deepak Kumar. 2023. “Integrated Network Pharmacology and In-Silico Approaches to Decipher the Pharmacological Mechanism of Selaginella Tamariscina in the Treatment of Non-Small Cell Lung Cancer.” Phytomedicine Plus, January 31, 2023, 100419.
Saptamita Paul Choudhury, Sarika Bano, Srijon Sen, Kapil Suchal, Saroj Kumar, Fredrik Nikolajeff, Sanjay Kumar Dey, Vaibhav Sharma. 2022. “Altered Neural Cell Junctions and Ion-channels Leading to Disrupted Neuron Communication in Parkinson’s Disease”. npj Parkinson's Disease. 8 (1): 1–24. (IF: 8.085)
Rajkumar Kulandaisamy, Tushar Kushwaha, Anu Dalal, Vikas Kumar, Deepa Singh, Kamal Baswal, Pratibha Sharma, Kokkula Praneeth, Pankaj Jorwal, Sarala R Kayampeta, Tamanna Sharma, Srinivas Maddur, Manoj Kumar, Saroj Kumar, Aparoy Polamarasetty, Aekagra Singh, Deepak Sehgal, Shivajirao L Gholap, Mohan B Appaiahgari, Madhumohan R Katika, Krishna K Inampudi. 2022. “Repurposing of FDA Approved Drugs Against SARS-CoV-2 Papain-Like Protease: Computational, Biochemical, and In Vitro Studies.” Frontiers in Microbiology 13: 877813. (IF: 5.640)
Nithin KV, Kumar S, Koli DK*. 2021. Comparative evaluation of Osteocalcin in peri-implant crevicular fluid and radiographic bone loss of immediate loading and delayed loading dental implants: a preliminary split-mouth randomized control trial. Koli, International Journal of Prosthodontics 35 (2): 174–180. (IF: 1.785)
Singh Y, Kumar N, Khushbu P, Chauhan BS, Shankar G, Kumar S, Singh G, Srikrishna S, Garg P, Singh G, Rai G, Modi GP*. 2022. Exploration of Neuroprotective Properties of Naturally Inspired Multifunctional Molecule (F24) Against Oxidative Stress and Amyloid β Induced Neurotoxicity in Alzheimer's Disease Models. ACS Chemical Neuroscience. 13 (1): 27-42 (IF: 5.780)
Simran Rastogi, Vaibhav Sharma, Prahalad Singh Bharti, Komal Rani, Gyan P. Modi, Fredrik Nikolajeff, and Saroj Kumar*. 2021. “The Evolving Landscape of Exosomes in Neurodegenerative Diseases: Exosomes Characteristics and a Promising Role in Early Diagnosis.” International Journal of Molecular Sciences 22 (1): 440. (IF: 5.923)
Komal Rani, Simran Rastogi, Poorvi Vishwakarma, Prahalad Singh Bharti, Vaibhav Sharma, Km Renu, Gyan P. Modi, Venugopalan Y. Vishnu, Prashun Chatterjee, Aparajit Ballav Dey, Fredrik Nikolajeff, and Saroj Kumar*. 2021. “A Novel Approach to Correlate the Salivary Exosomes and Their Protein Cargo in the Progression of Cognitive Impairment into Alzheimer’s Disease.” Journal of Neuroscience Methods 347 (January): 108980. (IF: 2.390)
Lakshay Malhotra, Harsh K. V. Goyal, Sunita Jhuria, Kapil Dev, Saroj Kumar, Manoj Kumar, Punit Kaur, and Abdul S. Ethayathulla*. 2021. “Curcumin Rescue P53Y220C in BxPC-3 Pancreatic Adenocarcinomas Cell Line: Evidence-Based on Computational, Biophysical, and in Vivo Studies.” Biochimica et Biophysica Acta - General Subjects 1865 (2): 129807. (IF: 3.770)
Rajkumar Kulandaisamy, Tushar Kushwaha, Vikas Kumar, Soumya De, Saroj Kumar, Santosh Kumar Upadhyay, Manoj Kumar, Krishna K. Inampudi*. 2020. "Characterization of active/binding site residues of peptidyl-tRNA hydrolase using biophysical and computational studies". International Journal of Biological Macromolecules 159: 877-885. (IF: 6.953)
Vaibhav Sharma, Simran Rastogi, Kaushal Kumar Bhati, Alagiri Srinivasan, Ajoy Roychoudhury, Fredrik Nikolajeff, and Saroj Kumar*. 2020. “Mapping the Inorganic and Proteomic Differences among Different Types of Human Teeth: A Preliminary Compositional Insight.” Biomolecules 10 (11): 1540. (IF: 4.879)
Javeed Ahmad, Mohd Khubaib, Javaid Ahmad Sheikh, Rita Pancsa, Saroj Kumar, A. Srinivasan, M. Madan Babu, Seyed E. Hasnain*, and Nasreen Z. Ehtesham*. 2020. “Disorder-to-Order Transition in PE-PPE Proteins of Mycobacterium Tuberculosis Augments the pro-Pathogen Immune Response.” FEBS Open Bio 10: 70-85. (IF: 2.693)
Komal Rani, Ranjan Mukherjee, Ekta Singh, Sanjeev Kumar, Vaibhav Sharma, Poorvi Vishwakarma, Prahalad Singh Bharti, Fredrik Nikolajeff, Ashok Kumar Dinda, Vinay Goyal and Saroj Kumar*. 2019. “Neuronal Exosomes in Saliva of Parkinson’s Disease Patients: A Pilot Study.” Parkinsonism & Related Disorders. 67: 21-23. (IF: 4.36)
Vaibhav Sharma, Komal Rani, Ajoy Roychoudhury, Amita Chawla, Fredrik Nikolajeff and Saroj Kumar*. 2019. "Novel Insights into Regulation of Human Teeth Biomineralization: Deciphering the Role of Post-Translational Modifications in a Tooth Protein Extract." International Journal of Molecular Sciences. 20 (16): 4035. (IF: 5.923)
Das, Uddipan, Ekta Singh, Sudhaker Dharavath, Udaya Kumar Tiruttani Subhramanyam, Ravi Kant Pal, Ramachandran Vijayan, Saji Menon, Saroj Kumar, Samudrala Gourinath, and Alagiri Srinivasan. 2019. “Structural Insights into the Substrate Binding Mechanism of Novel ArgA from Mycobacterium Tuberculosis.” International Journal of Biological Macromolecules 125 (March): 970–78. (IF: 6.953)
Saibu, Yusuf, Saroj Kumar, Ankur Jamwal, Derek Peak, and Som Niyogi. 2018. “A FTIRM Study of the Interactive Effects of Metals (Zinc, Copper and Cadmium) in Binary Mixtures on the Biochemical Constituents of the Gills in Rainbow Trout (Oncorhynchus Mykiss).” Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP 211 (September): 48–56. (IF: 3.228)
Divekar, Monali Trimbak, Chithra Karunakaran, Rachid Lahlali, Saroj Kumar, Vellaichamy Chelladurai, Xia Liu, Ferenc Borondics, Saravanan Shanmugasundaram, and Digvir Singh Jayas. 2017. “Effect of Microwave Treatment on the Cooking and Macronutrient Qualities of Pulses.” International Journal of Food Properties 20 (2): 409–22. (IF: 2.727)
Lahlali, Rachid, Tao Song, Mingguang Chu, Fengqun Yu, Saroj Kumar, Chithra Karunakaran, and Gary Peng. 2017. “Evaluating Changes in Cell-Wall Components Associated with Clubroot Resistance Using Fourier Transform Infrared Spectroscopy and RT-PCR.” International Journal of Molecular Sciences 18 (10). (IF: 5.923)
Lahlali, Rachid, Tao Song, Mingguang Chu, Fengqun Yu, Linda Mcgregor, B Gossen, Saroj Kumar, Chithra Karunakaran, and Gary Peng. 2016. “Investigation on the Role of Molecular Composition and Lignification of Canola Plant Cell Wall in Resistance Mechanisms Associated with CR Gene Rcr1.” Phytopathology 106 (12): 145.
Lahlali, Rachid, Wang, L, Kumar, Saroj, Karunakaran, Chithra, Fobert, PR, Peng, Gary and Hallin, Emil L. 2015. Use of Fourier transform-infrared spectroscopy as a new method to study host resistance mechanism to fusarium head blight [Fusarium graminearum]. Canadian Journal of Plant Pathology. 37 (2): 248-252. (IF: 2.442)
Lahlali, Rachid, Yunfei Jiang, Saroj Kumar, Chithra Karunakaran, Xia Liu, Ferenc Borondics, Emil Hallin, and Rosalind Bueckert. 2014. “ATR–FTIR Spectroscopy Reveals Involvement of Lipids and Proteins of Intact Pea Pollen Grains to Heat Stress Tolerance.” Frontiers in Plant Science. 5:747 (IF: 5.753)
Patents
Saroj Kumar, Simran Rastogi, Komal Rani. 2022. “A Composition for Isolating Exosomes and Method Thereof”. Patent Application Number: 202211022537.
Gyan Prakash Modi, Himanshu Rai, Rishabh Singh, Saroj Kumar, Gauri Shankar, Brijesh Singh, Sarika Gupta, Saripella Srikrishna, Sairam Krishnamurthy. 2022. “An Imaging Probe for Detection of Key Biomarkers in Alzheimer's Disease”. Reference/identification number of the patent: 6457IN034.
Gyan Prakash Modi, Yash Pal Singh, C. Praveen Kumar, Meenu Yadav, Gauri Shankar, Gourav Singh, Saroj Kumar, S Srikrishna. 2021. “A multifunctional diarylurea-hydroxyamidine based compound for treatment of Alzheimer’s disease”. TEMP/E-1/1680/2021-DEL. Patent App. No: 202111001482; Ref. No. P.2116.IN.
Books/Monographs
S Kumar. Infrared spectroscopy: Method development and ligand binding to pyruvate kinase. 2011, pp 1-57, ISBN: 978-91-7447-297-4